- AC Hotel by Marriott Irvine
- Atrium Hotel Orange County
- Courtyard Irvine John Wayne Airport/Orange County
- Courtyard by Marriott Irvine Spectrum
- DoubleTree by Hilton Irvine-Spectrum
- Embassy Suites by Hilton Irvine Orange County Airport
- Extended Stay America Suites - Orange County - Irvine Spectrum
- Hampton Inn & Suites Irvine-Orange County Airport
- Hilton Garden Inn Irvine/Orange County Airport
- Hilton Irvine Orange County Airport
- Homewood Suites by Hilton Irvine John Wayne Airport
- Hyatt House Irvine/John Wayne Airport
- Hyatt Regency Irvine
- Irvine Marriott
- La Quinta Inn & Suites by Wyndham Irvine Spectrum
- Residence Inn Irvine John Wayne Airport Orange County
- Residence Inn by Marriott Irvine Spectrum
- Sonesta Irvine John Wayne Airport
- Sonesta Simply Suites Irvine Spectrum
- Springhill Suites Irvine John Wayne Airport / Orange County